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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP45
All Species:
17.88
Human Site:
S508
Identified Species:
30.26
UniProt:
Q70EL2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL2
NP_001073950
814
91733
S508
V
D
A
D
S
E
P
S
E
S
E
S
A
S
K
Chimpanzee
Pan troglodytes
XP_001139771
814
91702
S508
V
D
A
D
S
E
P
S
E
S
E
S
A
S
K
Rhesus Macaque
Macaca mulatta
XP_001085248
815
91829
S509
V
D
A
D
S
E
A
S
E
S
E
S
A
S
K
Dog
Lupus familis
XP_539054
796
87704
S500
A
D
A
D
S
E
A
S
E
P
S
S
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K387
813
90343
S507
V
D
A
D
S
E
A
S
E
P
E
I
A
S
K
Rat
Rattus norvegicus
Q2KJ09
826
93743
Q512
Q
T
E
L
C
A
N
Q
K
D
V
N
G
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506389
799
87920
C502
A
N
G
S
Q
T
D
C
S
E
R
E
V
S
H
Chicken
Gallus gallus
O57429
357
40913
M62
D
L
N
N
N
S
R
M
R
T
A
L
M
S
E
Frog
Xenopus laevis
Q6PAW2
901
101274
N513
L
S
T
L
E
N
G
N
E
E
S
A
D
G
L
Zebra Danio
Brachydanio rerio
A8HAL1
815
90431
K519
Q
E
D
L
S
L
E
K
H
N
E
D
Q
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121285
844
94413
T522
D
T
M
K
T
N
E
T
I
S
E
V
P
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790411
1122
123641
L536
E
A
S
V
L
D
R
L
S
N
A
G
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPT5
1083
120752
S613
E
A
S
S
S
F
I
S
S
D
H
E
Q
N
I
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
R177
H
S
N
N
C
K
V
R
S
P
D
K
C
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.4
72.2
N.A.
77.4
38.7
N.A.
63.7
20.1
38.5
38
N.A.
N.A.
29.3
N.A.
29.9
Protein Similarity:
100
99.7
96.6
81.5
N.A.
85.3
59.6
N.A.
75.5
29.7
56.4
56.6
N.A.
N.A.
49.1
N.A.
45.3
P-Site Identity:
100
100
93.3
53.3
N.A.
80
0
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
66.6
N.A.
80
20
N.A.
13.3
33.3
26.6
26.6
N.A.
N.A.
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.6
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
36
0
0
8
22
0
0
0
15
8
29
0
0
% A
% Cys:
0
0
0
0
15
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
15
36
8
36
0
8
8
0
0
15
8
8
8
8
15
% D
% Glu:
15
8
8
0
8
36
15
0
43
15
43
15
0
0
22
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
8
0
0
0
0
8
8
8
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
0
8
0
8
8
0
0
8
0
0
29
% K
% Leu:
8
8
0
22
8
8
0
8
0
0
0
8
0
8
8
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
8
15
15
8
15
8
8
0
15
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
15
0
0
22
0
0
8
8
0
% P
% Gln:
15
0
0
0
8
0
0
8
0
0
0
0
15
8
0
% Q
% Arg:
0
0
0
0
0
0
15
8
8
0
8
0
0
0
8
% R
% Ser:
0
15
15
15
50
8
0
43
29
29
15
29
15
50
8
% S
% Thr:
0
15
8
0
8
8
0
8
0
8
0
0
0
0
0
% T
% Val:
29
0
0
8
0
0
8
0
0
0
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _